Scientists from the UK are with the experimental therapy called 'Trojan horse' completely remove cancer from a mouse.
Scientists cancer cells have invaded from the tens of thousands of viruses that have come through the immune system to the tumor.
Using viruses to kill cancer cells is a new branch in tumor therapy, and one of the challenges is to get deep inside the tumor viruses so that they can act.
Researchers their study, published in the journal Cancer Research, rated this as 'exciting', but still need to do testing on humans.
After a 40-day 'Trojan horse' therapy, all mice that were used in the experiment were alive and their tumor was withdrawn.
Showing posts with label News. Show all posts
Showing posts with label News. Show all posts
Wednesday, December 26, 2012
Friday, May 4, 2012
National Cancer Research Month
Declared by the US Congress in 2007 and 2011, the American Association for Cancer Research, Philadelphia acknowledges May as National Cancer Research Month, in recognition of quality, innovative cancer research.
These two resolutions support efforts of the American Association for Cancer Research to facilitate progress and speed translation of latest scientific discoveries for the benefit of cancer victims and also the twelve million cancer survivors living in US today.
Watch video of Judy Garber, M.D., M.P.H., Past-president of American Association for Cancer Research, where she tells why cancer researchs is so important.
Some of research institutions, cancer centers, hospitals, advocacy groups, scientific societies, and other organizations that support National Cancer Research Month:
- American Society for Clinical Oncology
- American Society of Hematology
- American Society of Preventive Oncology
- American Society for Radiation Oncology
- Abramson Cancer Center of the University of Pennsylvania
- American Cancer Society Cancer Action Network
- American Childhood Cancer Organization
- American College of Radiology
- Association of American Cancer Institutes
- Arizona Cancer Center
- Barbara Ann Karmanos Cancer Institute
- Cancer Prevention Institute of California
- Cancer Therapy & Research Center, UT Health Science Center San Antonio
- Caring for Carcinoid Foundation
- Case Comprehensive Cancer Center
- C-Change
- City of Hope
- Cleveland Clinic Taussig Cancer Center
- Coalition of Cancer Cooperative Groups
- Dana-Farber Cancer Institute
- Duke Cancer Institute
- Fight Colorectal Cancer
- Fox Chase Cancer Center
- Fred Hutchinson Cancer Research Center
- Friends of Cancer Research
- Genetic Research Institute of the Desert
- Georgetown Lombardi Comprehensive Cancer Center
- Hollings Cancer Center
- Huntsman Cancer Institute
- Indiana University Melvin and Bren Simon Cancer Center
- International Cancer Advocacy Network
- International Myeloma Foundation
- Kimmel Cancer Center at Jefferson, Thomas Jefferson University and Hospitals
- Leukemia & Lymphoma Society
- Lustgarten Foundation
- Lung Cancer Foundation of America
- Lymphoma Research Foundation
- Mary Babb Randolph Cancer Center
- Massachusetts General Hospital Cancer Center
- Melanoma Research Alliance
- Memorial Sloan-Kettering Cancer Center
- Moffitt Cancer Center
- National Brain Tumor Society
- National Cancer Institute
- National Coalition for Cancer Research
- Norris Cotton Cancer Center
- North Carolina Central University
- OHSU Knight Cancer Institute
- Oncology Nursing Society
- OSU Comprehensive Cancer Center-James Cancer Hospital & Solove Research Institute
- Pancreatic Cancer Action Network
- Penn State Hershey Cancer Institute
- Prostate Cancer Foundation
- Robert H. Lurie Comprehensive Cancer Center
- Roswell Park Cancer Institute
- Sanford-Burnham Medical Research Institute
- The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
- Society of Gynecologic Oncology
- Stand Up To Cancer
- Stanford Cancer Center
- St. Jude Children's Research Hospital
- Susan G. Komen for the Cure® Advocacy Alliance
- The Cancer Institute at NYU Langone Medical Center
- The Cancer Institute of New Jersey
- The Carole and Ray Neag Comprehensive Cancer Center
- The Jackson Laboratory
- The Leukemia & Lymphoma Society
- The University of Chicago Comprehensive Cancer Center
- The University of Kansas Cancer Center
- The UNMC Eppley Cancer Center
- The University of Texas MD Anderson Cancer Center
- The V Foundation for Cancer Research
- The Wistar Institute
- UAB Comprehensive Cancer Center
- UAMS Winthrop P. Rockefeller Cancer Institute
- UCLA's Jonsson Comprehensive Cancer Center
- UCSF Helen Diller Family Comprehensive Cancer Center
- UC Cancer Institute and the Barrett Cancer Center
- UC Davis Cancer Center
- UCI Chao Family Comprehensive Cancer Center
- University of Colorado Cancer Center
- University of Florida Shands Cancer Center
- University of Hawai'i Cancer Center
- University of Illinois at Chicago Cancer Center
- University of Iowa Holden Comprehensive Cancer Center
- UK Markey Cancer Center
- University of Maryland Marlene and Stewart Greenebaum Cancer Center
- University of Michigan Comprehensive Cancer Center
- University of New Mexico Cancer Center
- UNC Lineberger Comprehensive Cancer Center
- University of Pittsburgh Cancer Institute
- USC Norris Comprehensive Cancer Center
- University of Virginia Cancer Center
- Vanderbilt-Ingram Cancer Center
- Vermont Cancer Center
- Yale Cancer Center
Please email tara.yates@aacr.org., if you want to support National Cancer Research Month.
Wednesday, April 4, 2012
Projection of mesothelioma mortality in UK
Projection of mesothelioma mortality in Britain using Bayesian methods.
Summary
Background:
Mesothelioma mortality has increased more than ten-fold over the past 40 years in Great Britain, with >1700 male deaths recorded in the British mesothelioma register in 2006. Annual mesothelioma deaths now account for >1% of all cancer deaths. A Poisson regression model based on a previous work by Hodgson et al has been fitted, which has allowed informed statistical inferences about model parameters and predictions of future mesothelioma mortality to be made.
Methods:
In the Poisson regression model, the mesothelioma cancer risk of an individual depends on the average collective asbestos dose for the individual in a given year and an age-specific exposure potential. The model has been fitted to the data within a Bayesian framework using the Metropolis-Hastings algorithm, a Markov Chain Monte Carlo technique, providing credible intervals for model parameters as well as prediction intervals for the number of future cases of mortality.
Results:
Males were most likely to have been exposed to asbestos between the ages of 30 and 49 years, with the peak year of asbestos exposure estimated to be 1963. The estimated number of background cases was 1.08 cases per million population.
Conclusion:
Mortality among males is predicted to peak at approximately 2040 deaths in the year 2016, with a rapid decline thereafter. Approximately 91 000 deaths are predicted to occur from 1968 to 2050 with around 61 000 of these occurring from 2007 onwards.
British Journal of Cancer advance online publication, 13 July 2010; doi:10.1038/sj.bjc.6605781 www.bjcancer.com.
Journal Details
Name: British journal of cancer
ISSN: 1532-1827
Summary
Background:
Mesothelioma mortality has increased more than ten-fold over the past 40 years in Great Britain, with >1700 male deaths recorded in the British mesothelioma register in 2006. Annual mesothelioma deaths now account for >1% of all cancer deaths. A Poisson regression model based on a previous work by Hodgson et al has been fitted, which has allowed informed statistical inferences about model parameters and predictions of future mesothelioma mortality to be made.
Methods:
In the Poisson regression model, the mesothelioma cancer risk of an individual depends on the average collective asbestos dose for the individual in a given year and an age-specific exposure potential. The model has been fitted to the data within a Bayesian framework using the Metropolis-Hastings algorithm, a Markov Chain Monte Carlo technique, providing credible intervals for model parameters as well as prediction intervals for the number of future cases of mortality.
Results:
Males were most likely to have been exposed to asbestos between the ages of 30 and 49 years, with the peak year of asbestos exposure estimated to be 1963. The estimated number of background cases was 1.08 cases per million population.
Conclusion:
Mortality among males is predicted to peak at approximately 2040 deaths in the year 2016, with a rapid decline thereafter. Approximately 91 000 deaths are predicted to occur from 1968 to 2050 with around 61 000 of these occurring from 2007 onwards.
British Journal of Cancer advance online publication, 13 July 2010; doi:10.1038/sj.bjc.6605781 www.bjcancer.com.
Journal Details
Name: British journal of cancer
ISSN: 1532-1827
Friday, March 23, 2012
New research findings on treatment of pleural mesothelioma
New findings of a recent research study are favoring a less extensive surgery treatment for patients of pleural mesothelioma cancer were recently published in an very important medical journal that tracks new developments in cancer research's. The recent study showed that a surgery called pleurectomy/decortications (P/D), in which surgeons remove part of the lungs lining and possibly part, but not all of a lung is more effective than a more extensive surgery.
Pleural mesothelioma is the most common type of asbestos-caused cancers that have killed hundreds of thousands of patients. It develops after people are exposed to asbestos fibres, usually in a their workplaces, and inhale very tiny particles of the material (asbestos). These tiny particles then slow work their way into the linings of a patients’s heart, lungs or abdominal organs and, over a several decades, create cancer cells which then form deadly malignant tumors.
The new findings, which were published in the April 2012 issue of the IASLC (International Association for the Study of Lung Cancer's) Journal of Thoracic Oncology, were posted on the UK Medical News Today, one of the leading in independent medical and health news websites.
The Medical News Today report said that victims with early stage pleural mesothelioma may be eligible for aggressive multi-modality therapy involving radiotherapy, chemotherapy and surgery and there has been a controversy over which of two main approaches is superior. One is called pleurectomy/decortication (P/D) involves a less extensive surgery, where surgeons remove just part of the lining around the lungs, potentially part, but not all, of the lung, and potentially part of the diaphragm and/or pericardium (membrane around the patients heart). The other approach, extrapleural pnemonectomy (EPP), a very extensive surgery where surgeons remove the entire diseased lung, lung lining (pleura), part of the membrane covering the victims heart and part of the diaphragm.
Website said that according to that study, "extrapleural pnemonectomy resulted in higher mortality and morbidity than pleurectomy/decortication, and pleurectomy/decortication resulted in significantly better survival in our experience as in others." The authors of this study "propose that pleurectomy/decortication becomes the standard surgical procedure offered as part of multi-modality therapy in pleural mesothelioma." Until recently, extrapleural pnemonectomy was the considered the standard of treatment. But this recent study along with other latest research seems to point to pleurectomy/decortication becoming the new standard of treatment in malignant pleural mesothelioma.
The Medical News Today said that Dr. Michael Weyant, assistant professor at the University of Colorado and thoracic surgeon, wrote an editorial in the April Journal of Thoracic Oncology about this topic. Dr. Michael Weyant concludes that, "the results of the recent study by Lang-Lazdunksi et al provide new data that should lead us to consider pleurectomy/decortication in all trials of treatment for malignant pleural mesothelioma. Based on this data it is too early to completely abandon extrapleural pnemonectomy altogether as there may be patient subsets where the potential reward outweighs the risks of the procedure."
MNT said the lead author of this work is Dr. Loïc Lang-Lazdunski, and co-authors include Dr. James Spicer and Dr. David Landau (King's College London).
In the US health officials say there are about 2,000 to 3,000 new cases of mesothelioma cancer diagnosed each year. Treatment of this rare form of cancer is difficult because just some of cases are diagnosed early enough to treat effectively. Published medical data shows that most patients are told they will have less than 18 months to live after being diagnosed with mesothelioma cancer.
Source
Resource4mesothelioma.com
Pleural mesothelioma is the most common type of asbestos-caused cancers that have killed hundreds of thousands of patients. It develops after people are exposed to asbestos fibres, usually in a their workplaces, and inhale very tiny particles of the material (asbestos). These tiny particles then slow work their way into the linings of a patients’s heart, lungs or abdominal organs and, over a several decades, create cancer cells which then form deadly malignant tumors.
The new findings, which were published in the April 2012 issue of the IASLC (International Association for the Study of Lung Cancer's) Journal of Thoracic Oncology, were posted on the UK Medical News Today, one of the leading in independent medical and health news websites.
The Medical News Today report said that victims with early stage pleural mesothelioma may be eligible for aggressive multi-modality therapy involving radiotherapy, chemotherapy and surgery and there has been a controversy over which of two main approaches is superior. One is called pleurectomy/decortication (P/D) involves a less extensive surgery, where surgeons remove just part of the lining around the lungs, potentially part, but not all, of the lung, and potentially part of the diaphragm and/or pericardium (membrane around the patients heart). The other approach, extrapleural pnemonectomy (EPP), a very extensive surgery where surgeons remove the entire diseased lung, lung lining (pleura), part of the membrane covering the victims heart and part of the diaphragm.
Website said that according to that study, "extrapleural pnemonectomy resulted in higher mortality and morbidity than pleurectomy/decortication, and pleurectomy/decortication resulted in significantly better survival in our experience as in others." The authors of this study "propose that pleurectomy/decortication becomes the standard surgical procedure offered as part of multi-modality therapy in pleural mesothelioma." Until recently, extrapleural pnemonectomy was the considered the standard of treatment. But this recent study along with other latest research seems to point to pleurectomy/decortication becoming the new standard of treatment in malignant pleural mesothelioma.
The Medical News Today said that Dr. Michael Weyant, assistant professor at the University of Colorado and thoracic surgeon, wrote an editorial in the April Journal of Thoracic Oncology about this topic. Dr. Michael Weyant concludes that, "the results of the recent study by Lang-Lazdunksi et al provide new data that should lead us to consider pleurectomy/decortication in all trials of treatment for malignant pleural mesothelioma. Based on this data it is too early to completely abandon extrapleural pnemonectomy altogether as there may be patient subsets where the potential reward outweighs the risks of the procedure."
MNT said the lead author of this work is Dr. Loïc Lang-Lazdunski, and co-authors include Dr. James Spicer and Dr. David Landau (King's College London).
In the US health officials say there are about 2,000 to 3,000 new cases of mesothelioma cancer diagnosed each year. Treatment of this rare form of cancer is difficult because just some of cases are diagnosed early enough to treat effectively. Published medical data shows that most patients are told they will have less than 18 months to live after being diagnosed with mesothelioma cancer.
Source
Resource4mesothelioma.com
Monday, March 12, 2012
Asbestos waste found in warehouse yard near High School
El Monte - Asbestos waste found in warehouse yard near Mountain View High School
EL MONTE - State environmental agencies have secured around 800 baggage of hazardous waste labeled as containing asbestos from an illegal waste transport facility located not far away of Mountain View High School.
Department of Toxic Substances Control and also the South Coast Air Quality Management District are investigating numerous violations at Titan Environmental Inc., 12432 Valley Blvd. The facility is located directly northwest of the school's soccer field and running track and has been operating since September last year.
State law prohibits any hazardous waste facility within five hundred feet of any school. Penalties include a $25,000 fine for every day of operation, according to the Department of Toxic Substances Control.
"They weren't supposed to be storing waste there. They were operating as a hazardous waste transporter and they didn't have the proper permits," said J.Garcia, spokesperson for the state DTSC, which regulates hazardous waste disposal and transport.
Fifteen air samples were taken by the AQMD in...more
Source: www.sgvtribune.com/
EL MONTE - State environmental agencies have secured around 800 baggage of hazardous waste labeled as containing asbestos from an illegal waste transport facility located not far away of Mountain View High School.
Department of Toxic Substances Control and also the South Coast Air Quality Management District are investigating numerous violations at Titan Environmental Inc., 12432 Valley Blvd. The facility is located directly northwest of the school's soccer field and running track and has been operating since September last year.
State law prohibits any hazardous waste facility within five hundred feet of any school. Penalties include a $25,000 fine for every day of operation, according to the Department of Toxic Substances Control.
"They weren't supposed to be storing waste there. They were operating as a hazardous waste transporter and they didn't have the proper permits," said J.Garcia, spokesperson for the state DTSC, which regulates hazardous waste disposal and transport.
Fifteen air samples were taken by the AQMD in...more
Source: www.sgvtribune.com/
Sunday, February 12, 2012
New asbestos cases - four mesothelioma lawsuits in St. Louis
Four new mesothelioma complaints were filed , at the end of last month, in the 22nd Judicial Circuit in the City of St. Louis.
Della-Croce, Kelly and Khodadadi will be represented by mesothelioma attorneys Christopher R. Guinn, Myles L. Epperson and William A. Kohlburn of Simmons, Browder, Gianaris, Angelides and Barnerd in Alton.
Pitrucha and Marsh will be represented by mesothelioma attorneys Aaron K. Dickey of Dickey Law Firm in St. Louis and by Devin C. McNulty and Troy Chandler of Williams, Kherkher, Hart and Boundas in Houston.
In her complaint, Della-Croce said the defendant companies caused her recently deceased husband, Albert Della-Croce, to develop mesothelioma cancer after his exposure to asbestos products throughout his career. The complaint does't indicate where Della-Croce resides, however it states that Albert worked as a driver, farmhand, refrigeration pipefitter and laborer in Colorado and California, according to the complaint.
Kathleen Kelly, in her complaint, said her mother, Anna Marie Kelly, developed mesothelioma cancer after she worked as a laborer , receptionist, clerical worker and ranch worker at several locations between 1976s and1992s. The mesothelioma lawsuit states, that she was also secondarily exposed to asbestos fibers through her ex-husband, T. Tegro, who worked as a laborer between 1976s and 1983s.
In her complaint, Khodadadi alleges she developed mesothelioma cancer after she worked as an financial and accounting analysis advisor from 1969 until now.
Pitrucha and Marsh allege their recently deceased father, Raymond Pitrucha Sr., developed lung cancer after his exposure to asbestos products throughout his career as a drywaller, laborer and sheetrocker between 1960s and 1990s throughout some of the midwestern states.
The suit alleges that the defendants should have known of the harmful effects of asbestos products, but failed to exercise reasonable care and caution for the plaintiff's safety.
As a result of their asbestos-related diseases, Anna Marie Kelly, Albert Della-Croce, Raymond Pitrucha Sr. and Khodadadi became disabled and disfigured, incurred medical costs and suffered great physical pain and mental anguish, the complaint says. In addition, they became prevented from pursuing their normal course of employment and, as a result, lost large sums of money that would have accrued to them, the plaintiffs claim.
Because of Albert Della-Croce's, Anna Marie Kelly's and Raymond Pitrucha Sr.'s deaths, their families have incurred funeral costs and have been deprived of their support and society.
In their four-count complaints, Louise Della-Croce, Kathleen Kelly and Khodadadi are seeking punitive and exemplary damages over $50,000 and actual and compensatory damages of more than $50,000.
In their four-count complaint, Marsh and Raymond Pitrucha Jr. are seeking actual and compensatory damages over $125,000 and punitive and exemplary damages over $50,000 and punitive damages in an adequate amount to deter Ferris Kimball Company from performing similar acts in the future, plus costs and other relief the court deems just.
(St. Louis Circuit Court case numbers: 12-L-408, 12-L-438 ,12-L-442, 12-L-443)
Source: "The Madison Record, New asbestos cases filed in St. Louis circuit court" Kelly Holleran, Feb. 08, 2012
You can find mesothelioma attorneys in our directory.
- Louise Della-Croce filed a lawsuit against 16 defendant corporations.
- Kathleen A. Kelly sued 39 defendant corporations.
- Khachick Khodadadi filed a lawsuit against 15 defendant corporation.
- Raymond Pitrucha Jr. and Rhonda Marsh of Missouri filed a lawsuit against 18 companies.
Della-Croce, Kelly and Khodadadi will be represented by mesothelioma attorneys Christopher R. Guinn, Myles L. Epperson and William A. Kohlburn of Simmons, Browder, Gianaris, Angelides and Barnerd in Alton.
Pitrucha and Marsh will be represented by mesothelioma attorneys Aaron K. Dickey of Dickey Law Firm in St. Louis and by Devin C. McNulty and Troy Chandler of Williams, Kherkher, Hart and Boundas in Houston.
In her complaint, Della-Croce said the defendant companies caused her recently deceased husband, Albert Della-Croce, to develop mesothelioma cancer after his exposure to asbestos products throughout his career. The complaint does't indicate where Della-Croce resides, however it states that Albert worked as a driver, farmhand, refrigeration pipefitter and laborer in Colorado and California, according to the complaint.
Kathleen Kelly, in her complaint, said her mother, Anna Marie Kelly, developed mesothelioma cancer after she worked as a laborer , receptionist, clerical worker and ranch worker at several locations between 1976s and1992s. The mesothelioma lawsuit states, that she was also secondarily exposed to asbestos fibers through her ex-husband, T. Tegro, who worked as a laborer between 1976s and 1983s.
In her complaint, Khodadadi alleges she developed mesothelioma cancer after she worked as an financial and accounting analysis advisor from 1969 until now.
Pitrucha and Marsh allege their recently deceased father, Raymond Pitrucha Sr., developed lung cancer after his exposure to asbestos products throughout his career as a drywaller, laborer and sheetrocker between 1960s and 1990s throughout some of the midwestern states.
The suit alleges that the defendants should have known of the harmful effects of asbestos products, but failed to exercise reasonable care and caution for the plaintiff's safety.
As a result of their asbestos-related diseases, Anna Marie Kelly, Albert Della-Croce, Raymond Pitrucha Sr. and Khodadadi became disabled and disfigured, incurred medical costs and suffered great physical pain and mental anguish, the complaint says. In addition, they became prevented from pursuing their normal course of employment and, as a result, lost large sums of money that would have accrued to them, the plaintiffs claim.
Because of Albert Della-Croce's, Anna Marie Kelly's and Raymond Pitrucha Sr.'s deaths, their families have incurred funeral costs and have been deprived of their support and society.
In their four-count complaints, Louise Della-Croce, Kathleen Kelly and Khodadadi are seeking punitive and exemplary damages over $50,000 and actual and compensatory damages of more than $50,000.
In their four-count complaint, Marsh and Raymond Pitrucha Jr. are seeking actual and compensatory damages over $125,000 and punitive and exemplary damages over $50,000 and punitive damages in an adequate amount to deter Ferris Kimball Company from performing similar acts in the future, plus costs and other relief the court deems just.
(St. Louis Circuit Court case numbers: 12-L-408, 12-L-438 ,12-L-442, 12-L-443)
Source: "The Madison Record, New asbestos cases filed in St. Louis circuit court" Kelly Holleran, Feb. 08, 2012
You can find mesothelioma attorneys in our directory.
Monday, December 12, 2011
Actor Harold Hopkins passed away from Mesothelioma
Harold Hopkins, 69 year old Australian actor dies in Neringah Private Hospital in Wahroonga, north Sydney on 11 December 2011, following a battle with mesothelioma cancer. His family thinks that he was exposed to asbestos fibres without protective clothing or masks on his first job after he finished high school. Harold took up asbestos sheeting as an apprentice carpenter in Queensland, in the early 1960s.
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